PATHOGENIC PROPERTIES OF GENETICALLY MODIFIED MICROORGANISM ASSESSMENT AS ONE OF THE CRITERIA OF BIOSAFETY
- 作者: Sheina N.I.1
-
隶属关系:
- N.I. Pirogov Russian National Research Medical University, 1, Ostrovitaynova str. Moscow
- 期: 卷 96, 编号 3 (2017)
- 页面: 284-286
- 栏目: EXPERIMENTAL INVESTIGATIONS
- ##submission.datePublished##: 21.10.2020
- URL: https://edgccjournal.org/0016-9900/article/view/640641
- DOI: https://doi.org/10.47470/0016-9900-2017-96-3-284-286
- ID: 640641
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In the experiment there were studied pathogenic properties of the 10 genetically-modified E.coli strains and S. cerevisiae in terms of virulence, toxicity and toxigenicity, invasiveness and ability to the dissemination. Most of studied strains were shown to have no pathogenic properties and be able therefore to be recommended for the use in biotechnology. Along with this 2 strain of E.coli DLT1270 2 and E.coli ECR-HIS-T had a highly invasive properties and therefore can be a dangerous for warm-blooded animals and humans.
作者简介
N. Sheina
N.I. Pirogov Russian National Research Medical University, 1, Ostrovitaynova str. Moscow
编辑信件的主要联系方式.
Email: ni_sheina@mail.ru
俄罗斯联邦
参考
- Ермишин А.П. Генетически модифицированные организмы: мифы и реальность. Минск: Тэхналогiя; 2004.
- Ермишин А.П., ред. Биотехнология. Биобезопасность. Биоэтика. Минск: Тэхналогiя; 2005.
- ВП-П8-2322. Комплексная программа развития биотехнологий в Российской Федерации на период до 2020 г. М.; 2012.
- Пивоваров Ю.П., Мялина Л.И., Королик В.В. Критерии оценки патогенных свойств штаммов-продуцентов, предлагаемых для использования в промышленности микробиологического синтеза: Методические рекомендации. М.; 1992.
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