电邮这篇文章 Effect of nanocluster polyoxometalate {mo72fe30} on morphofunctional state of macrophages in cultures
- 作者: Titova S.A.1, Tonkushina M.O.1, Grzhegorzhevskii K.V.1, Danilova I.G.1,2, Pozdina V.A.2, Ulitko M.V.1, Ostroushko A.A.1
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隶属关系:
- Ural Federal University named after the First President of Russia B. N. Yeltsin
- Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences
- 期: 卷 66, 编号 4 (2024)
- 页面: 367-379
- 栏目: Articles
- URL: https://edgccjournal.org/0041-3771/article/view/669501
- DOI: https://doi.org/10.31857/S0041377124040053
- EDN: https://elibrary.ru/QCQFVM
- ID: 669501
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The aim of this work was to study the effect of nanocluster polyoxometalate {Mo72Fe30} on the macrophage link of the immune system. In vitro studies of polyoxometalate on macrophage cultures allowed us to evaluate the reaction of immune system cells (in particular, peritonial and alveolar macrophages) to nanoparticles. The analysis of the obtained data allowed to establish that {Mo72Fe30} is not toxic for peritonial and alveolar macrophages, has no significant effect on the morphology of cells, as well as on the activity of α-naphthylacetate esterase. However, it significantly reduces phagocytic activity when cells are cultured with POM, which may indicate possible polarisation of macrophages. The obtained results confirm the possibility of using {Mo72Fe30} in the field of biomedicine.
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作者简介
S. Titova
Ural Federal University named after the First President of Russia B. N. Yeltsin
编辑信件的主要联系方式.
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg
M. Tonkushina
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg
K. Grzhegorzhevskii
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg
I. Danilova
Ural Federal University named after the First President of Russia B. N. Yeltsin; Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg; Ekaterinburg
V. Pozdina
Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg
M. Ulitko
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg
A. Ostroushko
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
俄罗斯联邦, Ekaterinburg
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