Modern technologies to produce radionuclides for nuclear medicine

V. I. Zherebchevsky; Жеребчевский В. И.; I. E. Alekseev; Алексеев И. Е.; N. A. Maltsev; Мальцев Н. А.; V. V. Petrov; Петров В. В.; N. A. Prokofiev; Прокофьев Н. А.; E. O. Zemlin; Землин Е. О.; S. Yu. Torilov; Торилов С. Ю.

doi:10.31857/S0367676523702149

Modern technologies to produce radionuclides for nuclear medicine

Autores: Zherebchevsky V.I.¹, Alekseev I.E.², Maltsev N.A.¹, Petrov V.V.¹, Prokofiev N.A.¹, Zemlin E.O.¹, Torilov S.Y.¹
Afiliações:
1. Saint Petersburg State University
2. Khlopin Radium Institute
Edição: Volume 87, Nº 8 (2023)
Páginas: 1198-1209
Seção: Articles
URL: https://edgccjournal.org/0367-6765/article/view/654645
DOI: https://doi.org/10.31857/S0367676523702149
EDN: https://elibrary.ru/ZDISPS
ID: 654645

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Arquivos suplementares
Estatísticas

Resumo

We discussed nuclear technologies to produce radioactive isotopes, with a focus on radionuclides used as radiopharmaceuticals in novel methods of cancer diagnosis and radionuclide therapy—theranostics. New target materials and nuclear reactions to produce these radionuclides were considered. The experimental and theoretical results of excitation functions of reactions (p, xn) studies in energy range 6–80 MeV for medium mass nuclear systems to produce radionuclides: scandium, technetium, antimony, terbium are presented. These radionuclides are promising for their use in nuclear medicine methods for diagnostics, therapy and theranostics.

Bibliografia

https://www.who.int/news-room/fact-sheets/detail/ cancer.
Жеребчевский В.И. // СПбГУ. 2020. № 6(3926). С. 29.
Sharp P.F., Gemmell H.G., Murray A.D. Practical nuclear medicine. 3rd ed. London: Springer-Verlag, 2005. 382 p.
Volterrani D., Erba P.A., Carrió I. et al. Nuclear medicine: methodology and clinical applications. V. 1. Springer, 2019. 1331 p.
Жеребчевский В.И., Алексеев И.Е., Лазарева Т.В. и др. // Изв. РАН. Сер. физ. 2021. Т. 85. № 10. С. 1452; Zherebchevsky V.I., Alekseev I.E., Lazareva T.V. et al. // Bull. Russ. Acad. Sci. Phys. 2021. V. 85. No. 10. P. 1128.
Zherebchevsky V., Alekseev I., Krymov E. et al. // Proc. LXX Intern. Conf. “NUCLEUS-2020” (Saint-Petersburg, 2020). P. 9.
Zherebchevsky V., Alekseev I., Lazareva T. et al. // Proc. LXXI Intern. Conf. “NUCLEUS-2021” (Saint Petersburg, 2021). P. 13.
Zherebchevsky V., Alekseev I., Feofilov G. et al. // Proc. LXXII Intern. Conf. “NUCLEUS-2022” (Moscow, 2022). P. 33.
Conti M., Bendriem B. // Clin. Transl. Imaging. 2019. V. 7. P. 139.
Lang C., Habs D., Parodi K., Thirolfa P.G. // JINST. 2014. V. 9. Art. No. P01008.
Gallego Manzano L., Abaline J.M., Acounis S. et al. // Nucl. Instrum. Meth. Phys. Res. A. 2018. V. 912. P. 329.
Rosar F., Buchholz H.-G., Michels S. et al. // EJNMMI Phys. 2020. V. 7. Art. No. 16.
Rosar F., Bohnenberger H., Moon E.S. et al. // Appl. Radiat. Isot. 2021. V. 170. Art. No. 109599.
Khawar A., Eppard E., Sinnes J.P. et al. // Clin. Nucl. Med. 2018. V. 43. P. 486.
Langbein T., Weber W.A., Eiber M. // J. Nucl. Med. 2019. V. 60. No. 9 (Suppl. 2). P. 13S.
Yordanova A., Eppard E., Kürpig S. et al. // Onco. Targets Ther. 2017. V. 10. P. 4821.
Ferrari C., Niccoli Asabella A., Villano C. et al. // BioMed Res. Int. 2015. V. 2015. Art. No. 129764.
https://www.nndc.bnl.gov/nudat.
https://indico.cern.ch/event/689358/book-of-abstracts.pdf.
Müller C., Zhernosekov K., Köster U. et al. // J. Nucl. Med. 2012. V. 53. No. 12. P. 1951.
Baum R.P., Singh A., Benešová M. et al. // Dalton Trans. 2017. V. 46. P. 14638.
Müller C., Vermeulen C., Köster U. et al. // EJNMMI Radiopharm. Chem. 2016. V. 1. Art. No. 5.
Umbricht C.A., Köster U., Bernhardt P. et al. // Sci. Reports. 2019. V. 9. Art. No. 17800.
Borgna F., Haller S., Rodriguez J.M.M. et al. // Eur. J. Nucl. Med. Mol. Imaging. 2022. V. 49. P. 1113.
Baum R.P., Singh A., Kulkarni H.R. et al. // J. Nucl. Med. 2021. V. 62. No. 10. P. 1391.
Gómez-Tejedor G.G., Fuss M.C. Radiation damage in biomolecular systems. Dordrecht, Heidelberg, London, New York: Springer, 2012. 524 p.
The supply of medical radioisotopes: review of potential molybdenum-99/technetium-99m production technologies. Report OECD Nuclear Energy Agency, 2010.
Martinez Palenzuela Y., Barozier V., Chevallay E. et al. // Front. Med. 2021. V. 8. Art. No. 689281.
https://www.prismap.eu/about/project.
Жеребчевский В.И., Алексеев И.Е., Гриднев К.А. и др. // Изв. РАН. Сер. физ. 2016. Т. 80. № 8. С. 975; Zherebchevsky V.I., Alekseev I.E., Gridnev K.A. et al. // Bull. Russ. Acad. Sci. Phys. 2016. V. 80. No. 8. P. 888.
van der Meulen N.P., Hasler R., Talip Z. et al. // Molecules. 2020. V. 25. Art. No. 4706.
Filosofov D.V., Loktionova N.S., Rösch F. // Radiochim. Acta. 2010. V. 98. No. 3. P. 149.
Alliot C., Kerdjoudj R., Michel N. et al. // Nucl. Med. Biol. 2015. V. 42. No. 6. P. 524.
Guertin A., Nigron E., Sitarz M. et al. // Proc. 15th Intern. Conf. NRM. V. 1. (Varenna, 2018). P. 355.
Pupillo G., Mou L., Martini P. et al. // Proc. 15th Intern. Conf. NRM. V. 1. (Varenna, 2018). P. 341.
Fontana A., Calzaferri S., Canton L. et al. // Proc. 15th Intern. Conf. NRM. V. 1. (Varenna, 2018). P. 349.
Koning A.J., Delaroche J.P. // Nucl. Phys. A. 2003. P. 231.
Kalbach C. // J. Physics G. 1999. V. 25. P. 75.
Koning A.J., Hilaire S., Duijvestijn M.C. // Proc. Int. Conf. ND 2007. (Nice, 2007). P. 211.
Otuka N., Dupont E., Semkova V. et al. // Nucl. Data Sheets. 2014. V. 120. P. 272.
De Waal T.J., Peisach M., Pretorius R. // J. Inorg. Nucl. Chem. 1971. V. 33. P. 2783.
Krajewski S., Cydzik I., Abbas K. et al. // Radiochim. Acta. 2013. V. 101. P. 333.
Carzaniga T.S., Auger M., Braccini S. et al. // Appl. Radiat. Isot. 2017. V. 129. P. 96.
Sevior M.E., Mitchell L.W., Anderson M.R. et al. // Aust. J. Phys. 1983. V. 36. P. 463.
Liang H., Han Y., Shen Q. // Nucl. Instrum. Meth. Phys. Res. B. 2011. V. 269. P. 597.
https://www-nds.iaea.org/medical.
Kalbach C. // Phys. Rev. C. 2005. V. 71. Art. No. 034606.
Blann M. // Nucl. Phys. A. 1973. V. 213. P. 570.
Qaim S.M., Sudár S., Scholten B. et al. // Appl. Radiat. Isot. 2014. V. 85. P. 101.
Tárkányi F., Hermanne A., Takács S. et al. // J. Radioanalyt. Nucl. Chem. 2013. V. 298. P. 1385.
Avrigeanu M., Rochman D., Koning A.J. et al. // Eur. Phys. J. A. 2022. V. 58. Art. No. 3.