New Bacteriophage Pseudomonas Phage Ka1 from a Trivia of Lake Baikal
- Autores: Fedorova M.S.1, Gatina A.E.1, Ilyina V.N.1, Yadykova L.L.1, Dryukker V.V.2, Gorshkova A.S.2, Kayumov A.R.1, Trizna E.Y.1
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Afiliações:
- Kazan (Volga Region) Federal University
- Limnological Institute, Siberian Branch of the Russian Academy of Sciences
- Edição: Volume 93, Nº 4 (2024)
- Páginas: 474-480
- Seção: SHORT COMMUNICATIONS
- URL: https://edgccjournal.org/0026-3656/article/view/655098
- DOI: https://doi.org/10.31857/S0026365624040126
- ID: 655098
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Resumo
The bacteriophage Pseudomonas phage Ka1 was isolated from the water of a tributary of Lake Baikal, in the area of discharge of treated wastewater in the city of Slyudyanka. The bacteriophage genome is 46,092 bp in size. and 50% composition of G + C pairs (AN OP455935.1) has 91% identity with the genome of Pseudomonas phage PSA37, belonging to the Bruynoghevirus from the class Caudoviricetes, which characterizes it as a new representative of Luz24-like phages (Bruynoghevirus). The bacteriophage lyses 62% of clinical isolates of Pseudomonas aeruginosa and is able to increase the effectiveness of gentamicin, ciprofloxacin, imipinem and meropenem by 4–8 times against this bacterium. Integrases, transposases and recombinases are not identified in the genome, which makes Pseudomonas phage Ka1 possible for use in complex therapy of infections caused by P. aeruginosa.
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Sobre autores
M. Fedorova
Kazan (Volga Region) Federal University
Autor responsável pela correspondência
Email: MaSFedorova97@mail.ru
Rússia, 420008, Kazan
A. Gatina
Kazan (Volga Region) Federal University
Email: MaSFedorova97@mail.ru
Rússia, 420008, Kazan
V. Ilyina
Kazan (Volga Region) Federal University
Email: MaSFedorova97@mail.ru
Rússia, 420008, Kazan
L. Yadykova
Kazan (Volga Region) Federal University
Email: MaSFedorova97@mail.ru
Rússia, 420008, Kazan
V. Dryukker
Limnological Institute, Siberian Branch of the Russian Academy of Sciences
Email: MaSFedorova97@mail.ru
Rússia, 664033, Irkutsk
A. Gorshkova
Limnological Institute, Siberian Branch of the Russian Academy of Sciences
Email: MaSFedorova97@mail.ru
Rússia, 664033, Irkutsk
A. Kayumov
Kazan (Volga Region) Federal University
Email: MaSFedorova97@mail.ru
Rússia, 420008, Kazan
E. Trizna
Kazan (Volga Region) Federal University
Email: MaSFedorova97@mail.ru
Rússia, 420008, Kazan
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