Peculiarities of the biological action of intense laser pulses at the molecular level

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Abstract

A biophysical model has been proposed for the formation of the main types of radiation damage to DNA in mammalian and human cells under action of intense femtosecond pulses in the visible and near-IR ranges.

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About the authors

A. N. Bugay

Joint Institute for Nuclear Research

Author for correspondence.
Email: bugay@jinr.ru
Russian Federation, Dubna

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2. Fig. 1. Calculation of the number of basic types of DNA damage per filament in a cell as a function of the peak intensity of a pulse with a wavelength of 0.8 μm, duration of 100 fs, and transverse radius of 1 μm. Solid line - base damage, dashed line - single-strand breaks, dashed line - DNA double-strand breaks

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3. Fig. 2. Calculation of the number of DNA DRs per filament in a cell as a function of the peak intensity of a 100 fs pulse with a duration of 100 fs and a transverse radius of 1 μm at different wavelengths: 0.6 μm (solid line), 0.8 μm (dashed line), 1 μm (dashed line)

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