Hematological parameters in workers of water supply facilities of petrochemical enterprises
- Authors: Karamova L.M.1, Vlasova N.V.1, Gainullina M.K.1, Masyagutova L.M.1,2
-
Affiliations:
- Ufa Research Institute of Occupational Medicine and Human Ecology
- Bashkir State Medical University
- Issue: Vol 101, No 9 (2022)
- Pages: 1029-1034
- Section: OCCUPATIONAL HEALTH
- Published: 08.10.2022
- URL: https://edgccjournal.org/0016-9900/article/view/638951
- DOI: https://doi.org/10.47470/0016-9900-2022-101-9-1029-1034
- ID: 638951
Cite item
Full Text
Abstract
Introduction. One of the major petrochemical complexes of the Republic of Bashkortostan is Limited liability company (LLC) «Gazprom Neftekhim Salavat». The normal operation of industrial enterprises requires the use of large volumes of water. Its water supply, water disposal, waste disposal, reclamation of sludge reservoirs, equipment repair, cleaning of oil sludge reservoirs is provided by LLC «PromVodoKanal». The main technological personnel are wastewater treatment operators, process plant operators, pumping plant operators, chemical analysis laboratory assistants, commodity operators. Their work is associated with exposure to harmful and / or dangerous production factors.
Objective. Search and substantiation of laboratory markers of early health disorders in workers of water supply facilities of petrochemical enterprises.
Materials and methods. Hygienic and clinical laboratory studies were carried out among workers of the main occupations of the «PromVodoKanal» station who have contact with various harmful derivative factors. A complex of hematological and biochemical research methods was used in the work.
Results. A comparative analysis of the frequency of occurrence of deviations of hematological parameters from the norm in all examined (occupational) groups was carried out. A laboratory study showed that hematological parameters are characterized by an increased content of hemoglobin, erythrocytes, and hematocrit. Changes in the mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC), and thrombocytes count, were detected in every fifth worker. Over the years of work, the share of workers with high levels of glucose and cholesterol increases markedly, the correlation of which reaches from 0.90 to 0.97.
Limitations. The article has limitations on the scientific study of working conditions, as periodic medical examinations are carried out by occupational pathologists.
Conclusions. Red blood values are specific markers of workers’ health problems and require special attention during periodic medical examinations.
Compliance with ethical standards. The research was conducted in accordance with the ethical standards of the Declaration of Helsinki 2000. Minutes of the meeting of the BEC dated March 10, 2022, No. 01-03.
Patient consent. Each participant of the study gave informed voluntary written consent to participate in the study and publish personal medical information in an impersonal form in the journal "Gigiena i Sanitariya (Hygiene and Sanitation, Russian journal)".
Contribution:
Karamova L.M. — concept and design of the study, writing the text;
Vlasova N.V. — collection and processing of material, writing the text;
Gainullina M.K. — editing;
Masyagutova L.M. — work with literary sources.
All authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.
Conflict of interest. The authors declare no conflict of interest.
Acknowledgement. The study had no sponsorship.
Received: May 25, 2022 / Accepted: August 04, 2022 / Published: September 30, 2022
About the authors
Lena M. Karamova
Ufa Research Institute of Occupational Medicine and Human Ecology
Author for correspondence.
Email: noemail@neicon.ru
ORCID iD: 0000-0003-0857-1150
Russian Federation
Natalya V. Vlasova
Ufa Research Institute of Occupational Medicine and Human Ecology
Email: vnv.vlasova@yandex.ru
ORCID iD: 0000-0002-8552-4756
MD, PhD, Ufa Institute of Occupational Health and Human Ecology, Ufa, 450106, Russian Federation.
e-mail: vnv.vlasova@yandex.ru
Russian FederationMahmuza K. Gainullina
Ufa Research Institute of Occupational Medicine and Human Ecology
Email: noemail@neicon.ru
ORCID iD: 0000-0001-9340-2284
Russian Federation
Lyaylya M. Masyagutova
Ufa Research Institute of Occupational Medicine and Human Ecology; Bashkir State Medical University
Email: noemail@neicon.ru
ORCID iD: 0000-0003-0195-8862
Russian Federation
References
- Yangulova G.A., Abizgil’dina R.R. Economic assessment of damage from water pollution by oil industry effluents on the example of «Gazprom Neftekhim Salavat». Vodoochistka. Vodopodgotovka. Vodosnabzhenie. 2012; (6): 68–70. (in Russian)
- Abazaev M.E. Environmental classification of water intakes. Al’manakh sovremennoy nauki i obrazovaniya. 2011; (2): 44–5. (in Russian)
- Valeev T.K., Suleymanov R.A., Rakhmatullin N.R. Estimation of risk for health of the population living in territories with developed petrochemistry and oil refining. Zdorov’e naseleniya i sreda obitaniya. 2014; (5): 6–8. (in Russian)
- Baktybaeva Z.B., Suleymanov R.A., Valeev T.K., Rakhmatullin N.R. Evaluation of oil refining and petrochemical industry impact on environmental and hygienic state of environmental objects and population health (literature review). Meditsina truda i ekologiya cheloveka. 2018; (4): 12–26. (in Russian)
- Krasovskiy V.O., Yakhina M.R. Management of sanitary supervision of occupational health at oil refineries and petrochemical plants (analytical review). Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2021; 100(3): 246–53. https://doi.org/10.47470/0016-9900-2021-100-3-246-253 (in Russian)
- Karmazinov F.V., Probirskiy M.D., Pulin O.V., Ignatchik V.S., Ilin Yu.A., Ignatchik S.Yu. Computerized wastewater treatment control systems. Vodosnabzhenie i sanitarnaya tekhnika. 2004; (4–1): 35–8. (in Russian)
- Karimova L.K., Zotova T.M., Mavrina L.N., Beygul N.A., Yakhina R.R., Valeeva E.T. Risk factors in organic synthesis manufacturing. Byulleten’ Vostochno-Sibirskogo nauchnogo tsentra Sibirskogo otdeleniya Rossiyskoy akademii meditsinskikh nauk. 2009; (1): 34–8. (in Russian)
- Timasheva G.V., Valeeva O.V. Diagnostic value of biochemic and hematologic changes in petrochemical industry workers. Meditsina truda i promyshlennaya ekologiya. 2009; (11): 20–3. (in Russian)
- Timasheva G.V., Bakirov A.B., Valeeva E.T., Karimova L.K., Masyagutova L.M. The laboratory markers of early metabolic disorders in workers of industrial rubber articles. Klinicheskaya laboratornaya diagnostika. 2015; 60(7): 31–5. (in Russian)
- Shvachko A.E., Marinin S.Yu. Assessment of professional risks for employees of Vodokanal LLC st. Dinskaya. Alleya nauki. 2019; 3(12): 953–66. (in Russian)
- Terin A.A. Analysis of the labor protection management system in the municipal unitary enterprise «Vodokanal». Vestnik nauki i obrazovaniya. 2020; (7–1): 21–4. (in Russian)
- Kuz’mina O.V., Iskakova A.K. Analysis of occupational morbidity in the organization under study. Molodoy uchenyy. 2016; (26): 52–5. (in Russian)
- Ershov V.I. Visual Hematology [Naglyadnaya gematologiya]. Moscow: GEOTAR-Media; 2008. (in Russian)
- Hoffbrant A.V., Pettit J.E. Essential Hematology. Oxford: Blackwell Scientific Publ.; 1993.
- Kuznik B.I. Physiology and Pathology of the Blood System [Fiziologiya i patologiya sistemy krovi]. Moscow: Vuzovskaya kniga; 2004. (in Russian)
- Lewis S.M., Bane B., Bates E. Practical Haematology. Edinburgh: Churchill Livingstone; 1991.
- Lugovskaya S.A., Morozova V.T., Pochtar’ M.E., Dolgov V.V. Laboratory Hematology [Laboratornaya gematologiya]. Moscow: YuNIMED-press; 2002. (in Russian)
- Zyubina L.Yu., Shpagina L.A., Panacheeva L.A. Industrially mediated hemopathies and occupational diseases of blood. Meditsina truda i promyshlennaya ekologiya. 2008; (11): 15–20. (in Russian)
- Volkov V.S., Korichkina L.N. Phenomenon of endogenic auto-rosetting in blood, its role in toxic anemia pathogenesis. Meditsina truda i promyshlennaya ekologiya. 2006; (11): 39–41. (in Russian)
- Anoop K., Sasmal D., Amand B., Kunal M., Aman T., Neelima S. Deltamethrin-induced oxidative stress and mitochondrial caspase-dependent signaling pathways in murine splenocytes. Environ. Toxicol. 2016; 31(7): 808–19. https://doi.org/10.1002/tox.22091
- Karamova L.M., Krasovskiy V.O., Basharova G.R., Vlasova N.V. Features of the response of the blood system in phthalates production workers. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2018; 97(5): 449–55. https://doi.org/10.18821/0016-9900-2018-97-5-449-455 (in Russian)
Supplementary files
